Axiom-4: Shubhanshu Shukla starts microgravity research with experiment on skeletal muscle degradation - The Times of India

Edition IN English Weather Subscribe To TOI+ Sign In TOI Today's ePaper News Science News Axiom-4: Shubhanshu Shukla Starts Microgravity Research With Experiment On Skeletal Muscle Degradation Axiom-4: Shubhanshu Shukla starts microgravity research with experiment on skeletal muscle degradation TOI Science Desk / TIMESOFINDIA.COM / Jul 1, 2025, 13:00 IST Share AA + TEXT SIZE Small Medium Large Group Captain Shubhanshu Shukla is conducting vital microgravity research aboard the ISS as part of the Axiom-4 mission. He's leading experiments, including a study on muscle degradation, to understand how space affects the human body. This Indo-international collaboration, involving ISRO, NASA, and Axiom Space, marks a significant step for India in space-based life sciences. Group Captain Shubhanshu Shukla has officially begun his scientific mission aboard the International Space Station (ISS) as part of the Axiom-4 mission. On June 29, 2025, he initiated microgravity research, including a critical experiment on muscle degradation known as Myogenesis. The study, conducted in the Life Sciences Glovebox (LSG), aims to uncover how skeletal muscles deteriorate in space, a key health concern for astronauts. Shukla’s work is part of a broader Indo-international collaboration involving ISRO, NASA, and Axiom Space, marking a significant milestone in India’s growing footprint in space-based life sciences research. Studying muscle loss and brain function in space The Myogenesis experiment, proposed by Bengaluru-based Institute for Stem Cell Science and Regenerative Medicine (InStem), is one of seven ISRO-backed microgravity experiments selected for this mission. Using the ISS's Life Sciences Glovebox, Shukla is exploring how muscles degrade in space, a problem that affects astronauts on long-duration missions. By identifying the biological pathways of muscle deterioration, researchers aim to develop therapies for both astronauts and people with muscle-degenerative diseases on Earth. In parallel, the crew began the Cerebral Hemodynamics study, using ultrasound to observe how microgravity impacts blood circulation in the brain, with implications for treating stroke and hypertension. India’s growing role in space-based life sciences      by Taboolaby Taboola Sponsored LinksSponsored Links Promoted LinksPromoted Links You May Like Most People With a Car Loan Have Never Tried ThisAuto Approve Learn More Undo This mission marks a crucial step for India in developing a microgravity research ecosystem. ISRO has supported seven experiments from Indian R&D labs and academic institutions, all of which Shukla will help carry out during his 14-day stay. Alongside these, NASA and ISRO are collaborating on five joint science investigations and two in-orbit STEM demonstrations. Axiom Space reports that the Axiom-4 mission includes about 60 experiments from 31 countries, making it one of the most diverse scientific missions to date. With Shukla’s contributions, India is not only participating but helping lead efforts to understand the human body in space. About the Author TOI Science Desk The TOI Science Desk stands as an inquisitive team of journalists, ceaselessly delving into the realms of discovery to curate a captivating collection of news, features, and articles from the vast and ever-evolving world of science for the readers of The Times of India. Consider us your scientific companion, delivering a daily dose of wonder and enlightenment. Whether it's the intricacies of genetic engineering, the marvels of space exploration, or the latest in artificial intelligence, the TOI Science Desk ensures you stay connected to the pulse of the scientific world. At the TOI Science Desk, we are not just reporters; we are storytellers of scientific narratives. We are committed to demystifying the intricacies of science, making it accessible and engaging for readers of all backgrounds. Join us as we craft knowledge with precision and passion, bringing you on a journey where the mysteries of the universe unfold with every word. 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